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Dr. Farshid Sefat,
Associate Professor

Information about Dr. Farshid Sefat at the University of Bradford.

School of Engineering
(Faculty of Eng & Digital Technologies)
Email:
f.sefat1@bradford.ac.uk
Telephone:
+44 1274 233679
Photo of Dr. Farshid Sefat

Biography

Dr Farshid Sefat is Associate Professor and Programme Leader in Biomedical and Electronic Engineering Department at the University of Bradford (UK) and previously was head of Biomedical Engineering Department at King Faisal University (Saudi Arabia) and also a Visiting Professor at Stevens Institute of Technology (New Jersey, USA). He completed his post doctorate research assistant at University of Sheffield (UK) in the area of cornea tissue engineering. He received his Ph.D. (2011) and BEng. (2005) degrees from University of Bradford (UK) both in Biomedical Engineering mainly focus on bone cell engineering. He also obtained his MSc. (2006) in Cell and Tissue Engineering from Keele University (UK). His research is based on developing biomaterials to control cellular behaviour with particular emphasis in developing engineered materials for various tissue engineering applications. He is an author on >100 peer-reviewed journal articles, editorials and review papers and >30 book chapters/edited books. He is on the editorial boards and reviewer of >30 numerous journals including Materials Today, Acta Biomaterialia, IEEE, Bone, MDPI, Journal of Orthopaedics & Rheumatology, Materials Science and Engineering C, Journal of Biomechanics and many more.

Research

Key areas of research interest: 1. Skin, Hair, Breast and Cornea Tissue Engineering 2. Oral/Dental Tissue Engineering 3. Bone and Cartilage Cell Engineering 4. Dental Biomaterials 5. Biomaterials Fabrication & Characterization 6. Effect of Mechanical Stimulation on Bone Cell Behaviour 7. Effects of Growth Factors on Cell Behaviour (Cell Signalling) 8. Synthesis of Antibacterial Peptides for Dental Implant Modification Current research areas include: 1. Optimisation of layer-by-layer 3D scaffold for dermal wound healing 2. Fabrication and characterisation of biodegradable scaffolds for cornea tissue engineering 3. Cell signalling pathways of Transforming Growth Factor Beta (TGF-β isomers) 4. Investigating breast cancer behaviour using tissue engineering scaffolds 5. Electrospun nanofibers for vascular tissue engineering

Teaching

Details on teaching interests, highlights and modules are available for Dr. Farshid Sefat as follows:

Teaching interests

Regenerative MedicineBiomaterialsScaffold for Tissue EngineeringMathematics for Clinical TechnologiesCell culture TechniquesCell and Tissue BiologyDesign, Build, TestRadiology and Radiation Engineering

Teaching highlights

Skills of Biomedical EngineeringMaterials Technology and Structural MechanicsAnatomy & PhysiologyInfection Control

Publications

There are 25 publications involving or that are attributed to Dr. Farshid Sefat.

Peer Reviewed Journal

Dr. Farshid Sefat has 25 publication(s) listed under peer reviewed journal.
Title Year Publication name Journal Volume Pages Authors Editors ISSN Publisher DOI Location
Histatin peptides: Pharmacological functions and their applications in dentistry 2016 Khurshid, Z.; Najeeb, S.; Mali, M.; Moin, S.F.; Raza, S.Q.; Zohaib, S.; Sefat, Farshid; Zafar, M.S.
Production, Sterilisation and Storage of Biodegradable Electrospun PLGA Membranes for Delivery of Limbal Stem Cells to the Cornea 2013 Procedia Engineering 59 Sefat, F., McKean, R., Deshpande, P., Ramachandran, C., Hill, C., Sangwan, V., Ryan, A. and MacNeil, S.
The Effect of WIN55, 212-2 on Protein S100, Matrix Metalloproteinase-2 and Nitric Oxide Expression of Chondrocyte Monolayer 2017 Journal of Biomedical Engineering 3 Abdeldayem A, Youseffi M, Sefat F, Genedy M, Abdul Jamil, M.M., Javid F.
Fabrication and Characterisations of Hydrogels for Cartilage Repair 2017 Journal of tissue engineering and regenerative medicine 2 11. Kaur, P., Khaghani, S.A., Oluwadamilola, A., Khurshid, Z., Zafar, M.S., Mozafari, M., Youseffi, M and Sefat, F
Simplifying corneal surface regeneration using a biodegradable synthetic membrane and limbal tissue explants. 2013 Biomaterials 34 Deshpande P;Ramachandran C;Sefat F;Mariappan I;Johnson C;McKean R;Hannah M;Sangwan VS;Claeyssens F;Ryan AJ;MacNeil S; 1878-5905 10.1016/j.biomaterials.2013.03.064
Transplantation of adipose tissue-derived stem cells into brain through cerebrospinal fluid in rat models: Protocol development and initial outcome data. 2018 Current Stem Cell Research and Therapy Amini N;Vousooghi N;Alizade A;Ramezani S;Joghataei MT;Milan PB;Mehrabi S;Ababzadeh S;Sefat F;Mozafari M; 2212-3946 10.2174/1574888X13666180720112322
Comparison of biophysical properties characterized for microtissues cultured using microencapsulation and liquid crystal based 3D cell culture techniques 2018 Cytotechnology 70 13 - 29 Soon C.;Tee K.;Wong S.;Nayan N.;Sargunan Sundra;Ahmad M.;Sefat F.;Sultana N.;Youseffi M. 0920-9069 10.1007/s10616-017-0168-2
Biosynthetic PCL-graft-collagen bulk material for tissue engineering applications 2017 Gentile, P.; McColgan-Bannon, K.; Gianone, N.C.; Sefat, Farshid; Dalgarno, K.; Ferreira, A.M.
Shape-controlled silver NPs for shape-dependent biological activities 2017 Sadeghi, F.; Yazdanpanah, A.; Abrishamkar, A.; Moztarzadeh, F.; Ramedani, A.; Pouraghaie, S.; Shirinzadeh, H.; Samadikuchaksaraei, A.; Chauhan, N.P.S.; Hopkinson, L.; Sefat, Farshid; Mozafari, M.
Synthesis of Indolo[3,2-b]carbazoles via an Anomeric-Based Oxidation Process: A Combined Experimental and Computational Strategy 2018 Zolfigol, M.A.; Khazaei, A.; Karimitabar, F.; Hamidi, M.; Maleki, F.; Aghabarari, B.; Sefat, Farshid; Mozafari, M.
Imaging via widefield surface plasmon resonance microscope for studying bone cell interactions with micropatterned ECM proteins 2011 Journal of Microscopy 241 282 - 290 Sefat F.;Denyer M.;Youseffi M. 0022-2720 10.1111/j.1365-2818.2010.03430.x
Rapid creation of skin substitutes from human skin cells and biomimetic nanofibers for acute full-thickness wound repair 2015 Mahjour, S.B.; Fu, X.; Yang, X.; Fong, J.; Sefat, Farshid; Wang, H.
Transforming Growth Factor Beta (TGF-β): Natural Curing Agents for Repair 2014 Sefat, Farshid
Increasing elastin fibre production in a tissue engineered mesh for pelvic floor surgery 2014 Osman, N.; Roman, S.; Sefat, Farshid; Bullock, A.J.; Chapple, C.R.
Effect of transforming growth factor-β on up/down regulation of integrin-β1 in primary chondrocyte culture 2016 Khaghani, Seyed A.; Sefat, Farshid; Youseffi, Mansour; Rehman, R.; Soon, Chin Fhong; Akbarova, G.
Combination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration 2014 Ortega, Í.; Sefat, Farshid; Deshpande, P.; Paterson, T.; Ramachandran, C.; Ryan, A.J.; MacNeil, S.; Claeyssens, F.
Development of a Basement Membrane Substitute Incorporated Into an Electrospun Scaffold for 3D Skin Tissue Engineering 2014 Bye, F.J.; Bullock, A.J.; Singh, R.; Sefat, Farshid; Roman, S.; MacNeil, S.
Rocking Media Over Ex Vivo Corneas Improves This Model and Allows the Study of the Effect of Proinflammatory Cytokines on Wound Healing 2015 Deshpande, P.; Ortega, Í.; Sefat, Farshid; Sangwan, V.S.; Green, N.H.; Claeyssens, F.; MacNeil, S.
Dental Applications of Nanodiamonds 2016 Najeeb, S.; Khurshid, Z.; Agwan, A.S.; Zafar, M.S.; Alrahabi, M.; Bin Qasim, S.; Sefat, Farshid
Impact of packing and processing technique on mechanical properties of acrylic denture base materials 2015 Nejatian, T.; Sefat, Farshid; Johnson, T.
Transforming growth factor beta (TGF-β) isomers influence cell detachment of MG-63 bone cells 2015 Sefat, Farshid; Khaghani, Seyed A.; Nejatian, T.; Genedy, Mohamed A.; Abdeldayem, Ali I.A.; Moghaddam, Z.S.; Denyer, Morgan C.T.; Youseffi, Mansour
Potential of electrospun nanofibers for biomedical and dental applications 2016 Zafar, M.S.; Najeeb, S.; Khurshid, Z.; Vazirzadeh, M.; Zohaib, S.; Najeeb, B.; Sefat, Farshid
Effects of different transforming growth factor beta (TGF-β) isomers on wound closure of bone cell monolayers 2014 Sefat, Farshid; Denyer, Morgan C.T.; Youseffi, Mansour
Improved cell infiltration of electrospun nanofiber mats for layered tissue constructs 2016 Mahjour, S.B.; Sefat, Farshid; Polunin, Y.; Wang, L.; Wang, H.
Effect of Transforming Growth Factor-β3 on mono and multilayer chondrocytes 2016 Sefat, Farshid; Youseffi, Mansour; Khaghani, Seyed A.; Soon, Chin Fhong; Javid, Farideh A.