Dr. Goreti Ribeiro Morais,Lecturer in Medicinal Chemistry
Information about Dr. Goreti Ribeiro Morais at the University of Bradford.
- Institute of Cancer Therapeutics
(Faculty of Life Sciences) - Email:
- gribeiro@bradford.ac.uk
Biography
Goreti Ribeiro Morais obtained her degree in Pharmacy from the University of Coimbra and received her PhD in Pharmaceutical Chemistry from the University of Lisbon (Portugal)/University of Kyushu (Japan). Then she conducted a three-year postdoctoral stay at the Institute of Cancer Therapeutics (ICT), University of Bradford followed by a research scientist position at the Radiopharmaceutical Sciences Group/Technical University of Lisbon. In late 2014 she moved back at the ICT as senior PDRA to integrate the Yorkshire Cancer Research Programme grant. She made significant contributions towards three main medicinal chemistry projects (polysialyltransferase inhibitors, Cytochromes P450-activated prodrugs, and MMP-activated prodrugs) of the ICT and was crucial for the strengthening of the collaborations with Stanford University, Incanthera and Ellipses Pharma. Since 2019 she has played a key role in the successful Incanthera-funded doctoral Training centre (DTC-ICT). In addition to the training and mentoring of the medicinal chemistry postgraduate students of the ICT, she acted as formal co-supervisor of three PhD students (each successfully completed, and have secured excellent jobs in industry (2) and academia (1)) and three international undergraduate students. Currently she is co-supervisor of one PhD student and two MSc students. She has authored 50 peer-reviewed journal articles, 7 of which as corresponding author, 1 book chapter, 1 patent and 17 published abstracts in international conferences. Moreover, she has teaching responsibilities in three Master courses and holds a PAT role for MPharm students.
Professional activities
Information about education, employment and areas of particular interest for Dr. Goreti Ribeiro Morais is as follows:
Education
- University of Coimbra, Portugal - PGDipPharm
- University of Lisbon, Portugal - PhD Thesis
Employment
- University of Bradford - Senior Post-Doctoral Fellow in the year 2014 (specified as 06/10/2014)
Publications
There are 29 publications involving or that are attributed to Dr. Goreti Ribeiro Morais. They are listed as:
- chapter in book (1)
- peer reviewed journal (28)
Chapter in Book
Title | Year | Publication name | Journal | Volume | Pages | Authors | Editors | ISSN | Publisher | DOI | Location |
---|---|---|---|---|---|---|---|---|---|---|---|
Organometallic Chemistry of Rhenium and Technetium Fueled by Biomedical Applications | 2013 | ISBN: 9781118510148 | 10.1002/9781118742952.ch44 |
Peer Reviewed Journal
Title | Year | Publication name | Journal | Volume | Pages | Authors | Editors | ISSN | Publisher | DOI | Location |
---|---|---|---|---|---|---|---|---|---|---|---|
Dess–Martin periodinane-mediated oxidation of the primary alcohol of cytidine into a carboxylic acid | 2024 | Organic and Biomolecular Chemistry | 22 | Serre, A.R.E;Jha, V.;Rivault, A.;Eriksson, L.A.;Ribeiro Morais, G.;Falconer, R.A. | Royal Society of Chemistry | 10.1039/d4ob00240g | |||||
Azodicarboxylate-Mediated Peptide Cyclisation: Application to Disulfide Bond Formation in Solution and Solid Phase | 2023 | European Journal of Organic Chemistry | doi.org/10.1002/ejoc.202300789 | ||||||||
Cytochrome P450 Binding and Bioactivation of Tumor-Targeted Duocarmycin Agents | 2022 | Drug Metabolism and Disposition | doi.org/10.1124/dmd.121.000642 | ||||||||
Targeted delivery of a colchicine analogue provides synergy with ATR inhibition in cancer cells | 2022 | Biochemical Pharmacology | 10.1016/j.bcp.2022.115095 | ||||||||
An efficient assay for identification and quantitative evaluation of potential polysialyltransferase inhibitors | 2020 | The Analyst | doi.org/10.1039/D0AN00721H | ||||||||
Unravelling the antitumoral potential of novel bis(thiosemicarbazonato) Zn(II) complexes: structural and cellular studies | 2019 | Journal of Biological Inorganic Chemistry | 10.1007/s00775-018-1629-6 | ||||||||
Probing cytochrome P450 bioactivation and fluorescent properties with morpholinyl-tethered anthraquinones | 2018 | Bioorganic and Medicinal Chemistry Letters | 10.1016/j.bmcl.2018.03.040 | ||||||||
Synthesis and Biological Evaluation of Novel 2-Aryl Benzimidazoles as Chemotherapeutics Agents” | 2017 | Journal of Heterocyclic Chemistry | 10.1002/jhet.2575 | ||||||||
Biophysical Characterization and Antineoplastic Activity of New Bis(thiosemicarbazonato) Cu(II) Complexes | 2017 | Journal of Inorganic Biochemistry | 10.1016/j.jinorgbio.2016.11.026 | ||||||||
A Novel Theranostic Strategy for MMP-14–Expressing Glioblastomas Impacts Survival | 2017 | Molecular Cancer Therapeutics | 10.1158/1535-7163.MCT-17-0022 | ||||||||
Isostructural Re(I)/99mTc(I) Tricarbonyl Complexes Functionalized with Benzothiazole Derivatives for Cancer Theranostic | 2015 | Organic and Biomolecular Chemistry | 10.1039/c5ob00124b | ||||||||
The Tumor-Targeted Prodrug ICT2588 Demonstrates Therapeutic Activity Against Solid Tumors and Reduced Potential For Cardiovascular Toxicity | 2014 | Molecular Pharmaceutics | 10.1021/mp400760b | ||||||||
Steroid receptor ligands for breast cancer targeting: an insight into their potential role as PET imaging agents | 2013 | Current Medicinal Chemistry | 10.2174/092986713804806658 | ||||||||
Radiosynthesis and in vivo Evaluation of a 18F-Labelled Styryl-Benzoxazole Derivative for beta-Amyloid Targeting | 2013 | Applied Radiation and Isotopes | 10.1016/j.apradiso.2013.07.003 | ||||||||
Carbohydrate-based molecules suitable for nuclear molecular imaging | 2013 | European Journal of Organic Chemistry | 10.1002/ejoc.201201457 | ||||||||
Progesterona receptor targeting with radiolabelled steroids: an approach in predicting Breast Cancer Response to Therapy | 2013 | Journal of Steroid Biochemistry and Molecular Biology | 10.1016/j.jsbmb.2013.04.003 | ||||||||
Organometallic complexes for SPECT Imaging and/or Radionuclide Therapy | 2012 | Organometallics | 10.1021/om300501d | ||||||||
An optimized method for the synthesis of amino functionalized phosphatidylcholine | 2012 | Tetrahedron Letters | 10.1016/j.tetlet.2011.11.100 | ||||||||
A synthetic overview of radiolabeled compounds for β-amyloid targeting | 2012 | European Journal of Organic Chemistry | 10.1002/ejoc.201101449 | ||||||||
Synthesis and in vitro evaluation of fluorinated styryl benzazoles as amyloid-probes | 2011 | Bioorganic and Medicinal Chemistry | 10.1016/j.bmc.2011.09.065 | ||||||||
Acid catalysed reaction of indanones, tetralones and benzosuberone with neopentyl glycol and other alkanediols under forced conditions | 2010 | Journal of Chemical Research-S | 10.3184/030823410X12753214605445 | ||||||||
Acid catalysed reaction of estrones with neopentyl glycol under forced conditions | 2010 | Journal of Chemical Research-S | 10.3184/030823410X12678785299942 | ||||||||
Radioiodinated ligands for the estrogen receptor: effect of different 7-cyanoalkyl chains on the binding affinity of novel iodovinyl-6-dehydroestradiols | 2009 | Applied Radiation and Isotopes | 10.1016/j.apradiso.2008.10.005 | ||||||||
A facile preparation of thio-trehalose analogues – 1,1-thiodissacharides | 2009 | Carbohydrate Research | 10.1016/j.carres.2009.03.017 | ||||||||
Selective synthesis of Neu5Ac2en and its oxazoline derivative using BF3.Et2O | 2009 | Tetrahedron Letters | 10.1016/j.tetlet.2009.01.117 | ||||||||
Application of HOF·CH3CN to the synthesis of glycosyl sulphones | 2008 | Tetrahedron | 10.1016/j.tet.2008.05.033 | ||||||||
Efficient one-pot synthesis of glycosyl disulphides | 2007 | Tetrahedron Letters | 10.1016/j.tetlet.2007.08.106 | ||||||||
Simple amidation of non-protected phenol containing 2-alkenoic acids | 2005 | Journal of Chemical Research-S | 10.3184/030823405775146889 |